HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycerol → Apomorphine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycerol | HCID 753 | — |
| Reactant | 4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)- | HCID 9410 | — |
| Solvent | Water | HCID 962 | — |
| Product | Apomorphine | HCID 6005 | — |
Reaction Steps
The particulate apomorphine is combined with sodium carboxymethylcellulose and glycerol. The resulting mixture is mixed thoroughly (i.e., using a vacuum mixer) and homogenized. Water is added to the mixture (with extensive mixing) to form a hydrogel containing suspended nanoparticles of apomorphine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09044475B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-55d22e6600154d1b8fa38d6c3fc1a3b3 |
| Source note | uspto-grants-2015_06 |