Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 4-Methyl-3-(trifluoromethyl)bromobenzene | HCID 2775635 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 4-Bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene | HCID 53418031 | — |
반응 단계
4-Bromo-1-methyl-2-trifluoromethyl-benzene (3 g, 12.55 mmol), N-bromosuccinimide (2.68 g, 15.06 mmol, 1.2 eq) and dibenzoylperoxid (60 mg, 2.5 mmol, 0.02 eq) are stirred in carbon tetrachloride under ultraviolet light at reflux for 5 h. The reaction mixture is cooled to RT, filtered and the filtrate is concentrated in vacuo. The residue is carefully purified by chromatography (silicagel, pure hexanes) to afford the title compound as a colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08193189B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-88b928d7bc08411589c265e5fbf2bde4 |
| 출처 메모 | uspto-grants-2012_06 |