HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromoaniline → 2'-Chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromoaniline | HCID 7807 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | 4-Bromo-3-chloroaniline | HCID 88888 | — |
| Reactant | [2-Chloro-4-(trifluoromethyl)phenyl]boronic acid | HCID 2783251 | — |
| Product | 2'-Chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine | HCID 69133514 | — |
Reaction Steps
The title compound was prepared as described in Example 15 substituting 4-bromoaniline and (2-chloro-4-(trifluoromethyl)phenyl)boronic acid for 4-bromo-3-chloroaniline and (4-chlorophenyl)boronic acid, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045389B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-316590b8ced642e2b5f8ae846749ab41 |
| Source note | uspto-grants-2015_06 |