HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86627645, compound → HCID 86627646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86627645 | HCID 86627645 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86627646 | HCID 86627646 | 99.9% |
Reaction Steps
Crude 4-{5-chloro-2-[(2-chloro-pyridine-4-carbonyl)-amino]phenyl}-3,6-dihydro-2H-pyridine-1-carboxylic acid 1-chloro-ethyl ester (550 mg) was dissolved in methanol (25 ml) in and heated to reflux for 16 hours. Evaporation afforded the crude title product (465 mg). Retention Time HPLC 1.48 min; MS (ES+) 350, 348 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045422B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-c8e04b132df743a0942f2d288f65b82b |
| Source note | uspto-grants-2015_06 |