Dichloromethane → 2-(2,3-Dimethylphenyl)propanal

HRID 2167231Notes

Reaction equation

HRID 2167231 reaction equation
[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][CH:10]1C[O:11]1.Cl[CH2:14]Cl>>[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]([CH3:14])[CH:10]=[O:11]

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 20300557HCID 20300557, compound2×

Product 1

HCID 208317782-(2,3-Dimethylphenyl)propanalYield 100%

Procedure

2-(2,3-Dimethylphenyl)methyloxirane, compound of formula (XXII), prepared according to example 4 (0.84 g, 5.18 mmol), was dissolved in dry dichloromethane (50 mL) and powdered Cu(BF4)2 hydrate (318 mg) was added at room temperature. After 2 h at room temperature, the mixture was washed with water, dried over Na2SO4 and concentrated under reduced pressure to yield 0.84 g (100%) of the title product.

Workup

  1. washthe mixture was washed with water
  2. dry with materialdried over Na2SO4
  3. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-7a1cf98a4fb04b718d9246a870306c1d
Source dataset
uspto-grants-2015_06
Patent number
US09045433B2

Reaction notes

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