1-Naphthaldehyde → HCID 136247054, compound

Participants

Reaction Steps

Compound 17 was synthesized from 5-methoxy-2-aminobenzamide (9) (1.2 g, 7.3 mmol) and 1-naphthaldehyde (14) (1.1 g, 7.3 mmol): yield 1.5 g (70%); pale yellow needles; mp 174 to 175° C.; 1H NMR (DMSO-d6) δ 3.87 (3H, s, OCH3), 7.22-7.34 (2H, m, 2×ArH), 7.53-7.72 (5H, m, 5×ArH), 7.95-8.22 (3H, m, 3×ArH), 12.62 (1H, br s, NH) ppm; MS (ESI) m/z 302; Anal. (C19H14N2O2): C, H, N.

Provenance & Evidence