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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 216742Generated: October 26, 2026

Sodium borohydride → (8-Methyl-2-o-tolylquinolin-3-yl)methanol

https://huagongshe.com/reaction/216742

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 57707895HCID 57707895—
SolventTetrahydrofuranHCID 8028—
Product(8-Methyl-2-o-tolylquinolin-3-yl)methanolHCID 57707986—

Reaction Steps

Prepared according to Procedure B using 8-methyl-2-o-tolylquinoline-3-carbaldehyde (1.28 g, 4.9 mmol) and solid NaBH4 (278 mg, 1.5 eq) in THF (10 mL). After purification, (8-methyl-2-o-tolylquinolin-3-yl)methanol was obtained as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08193199B2
Source datasetuspto-grants-2012_06
ORD IDord-883701b19faf4168bee54f6a39eb4754
Source noteuspto-grants-2012_06