Acetonitrile → HCID 11705919, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0550 g, 0.187 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) was added 2-bromoethyl phenyl ether (0.060 g, 0.29 mmol). The solution was stirred at 60° C. for 16 h. The reaction was cooled down to room temperature and then diluted with ethyl acetate and hexane causing a solid to crash out of solution. This solid was filtered off, and washed with hexane to give the title compound (0.063 g, 67.6%). EI-MS m/z 414 (M+) Rt (1.94 min).

Provenance & Evidence