HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → Diethyl (2-bromoethyl)phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Product | Diethyl (2-bromoethyl)phosphonate | HCID 79218 | — |
Reaction Steps
Commercially available 1,2-dibromoethane (1.0 equiv.) and triethyl phosphite (1.0 equiv.) were heated with microwave irradiation at 160° C. for 20 minutes. The resulting residue was purified by reverse phase high performance liquid chromatography (HPLC) (0.035% TFA in ACN: 0.05% TFA in H2O, C18 column) to give diethyl 2-bromoethylphosphonate as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045470B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-d790666b891e43a8b48fc9c705eb04da |
| Source note | uspto-grants-2015_06 |