Bromine → HCID 13048358, compound

Participants

Reaction Conditions

Reaction Steps

To a chloroform (20 mL) solution of methyl 3-(4-methylphenyl)-3-oxopropanoate (1.0 g), bromine (0.12 mL) was added, and the resultant was stirred at 70° C. for 1 hour under sealed conditions. Then, bromine (0.12 mL) was further added thereto, and the resultant was further stirred at 70° C. for 1 hour under sealed conditions. The reaction solution was concentrated under reduced pressure to obtain the title compound (1.3 g) as a brown oil.

Provenance & Evidence