Bromine → HCID 89404163, compound

HRID 2167707Notes

Reaction equation

HRID 2167707 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][CH:13]=1)[C:7]([NH:9][CH3:10])=[O:8])(=[O:3])[CH3:2].[Br:14]Br>C(O)(=O)C>[Br:14][CH2:2][C:1]([C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][CH:13]=1)[C:7]([NH:9][CH3:10])=[O:8])=[O:3]

Participants

4

Reactant 2

HCID 24408BromineHCID 59128719HCID 59128719, compound

Product 1

HCID 89404163HCID 89404163, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

To an acetic acid (2.4 mL) solution of 3-acetyl-N-methylbenzamide (0.33 g), at room temperature, an acetic acid (0.30 mL) solution of bromine (95 μL) was added dropwise, and the resultant was stirred at room temperature for 3.5 hours and then stirred at 60° C. for 1 hour. The reaction solution was concentrated under reduced pressure and then dried to obtain the title compound (0.50 g) as a yellow oil.

Workup

  1. stirringstirred at 60° C. for 1 hour
  2. concentrationThe reaction solution was concentrated under reduced pressure
  3. customdried

Sources & evidence

ORD record
ord-8125c7aed1184f169bd52d9943bae66e
Source dataset
uspto-grants-2015_06
Patent number
US09045466B2

Reaction notes

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