HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfamide → HCID 89618812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfamide | HCID 82267 | — |
| Reactant | HCID 89618823 | HCID 89618823 | — |
| Product | HCID 89618812 | HCID 89618812 | — |
Reaction Steps
The title compound was prepared by the method substantially similar to that mentioned in Example-98, using 5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-N—((S)-pyrrolidin-3-yl)pyrazolo[1,5-a]pyridine-3-carboxamide (Example-82) and Sulfamide to afford the crude, which was purified by Preparative HPLC [Column: 21.2×250×7 um, Zorbax, XDB,C-18(#22), Mobile phase-A: 10 mmol.NH4OAc in water, B:ACN, Gradient (Time/% B): 0/30, 2/30, 8/90 and Flow rate:20 mL/min] to afford 26 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045479B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-5b7e4bd2e3b4409ebb0fe7624c904cb0 |
| Source note | uspto-grants-2015_06 |