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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2167899Generated: October 26, 2026

1H-Benzotriazole-1-methanol → 1-[2-(4-octyloxy-phenyl)-morpholin-4-ylmethyl]-1H-benzotriazole

https://huagongshe.com/reaction/2167899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Benzotriazole-1-methanolHCID 224169—
Reactant2-(4-Octyloxy-phenyl)-morpholineHCID 67032351—
SolventEthanolHCID 702—
Product1-[2-(4-octyloxy-phenyl)-morpholin-4-ylmethyl]-1H-benzotriazoleHCID 68193808—

Reaction Conditions

Temperature50 °C

Reaction Steps

To a solution of 2-(4-octyloxy-phenyl)-morpholine (0.75 g; 2.6 mmol) in EtOH (10 mL) was added 1H-benzotriazole-1-methanol (0.38 g; 2.6 mmol), and the reaction mixture was heated at 50° C. for 20 minutes. After cooling to RT, the solvent was removed in vacuo to afford 1-[2-(4-octyloxy-phenyl)-morpholin-4-ylmethyl]-1H-benzotriazole; which was used as such.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045441B2
Source datasetuspto-grants-2015_06
ORD IDord-d35483a8f226468e8a2efb39e1db68f7
Source noteuspto-grants-2015_06