Trifluoroacetic acid → HCID 71679680, compound

Participants

Reaction Steps

[2-(4-{7-[3-Cyano-4-(tetrahydro-pyran-4-yloxy)-phenyl]-furo[3,2-b]pyridin-2-yl}benzoyl-amino)-ethyl]-methyl-carbamic acid tert-butyl ester (59.0 mg, 0.1 mmol) is dissolved in dichloromethane (1 ml). Trifluoro-acetic acid (1 ml, 12.98 mmol) is added to the solution. The mixture is stirred for 16 h at room temperature. The solvent is removed in vacuum; yield: 20 mg 4-{7-[3-cyano-4-(tetrahydro-pyran-4-yloxy)-phenyl]-furo[3,2-b]pyridin-2-yl}-N-(2-methyl-amino-ethyl)-benzamide trifluoroacetate; HPLC/MS: 1.61 min, [M+H]=497;

Provenance & Evidence