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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2168572Generated: November 2, 2026

4-Chlorobenzylamine → 1-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid 4-chloro-benzylamide

https://huagongshe.com/reaction/2168572

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant(1-{9-[(4s,2r,3r,5r)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-n-(cyclopentylmethyl)carboxamideHCID 9933850—
Product1-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid 4-chloro-benzylamideHCID 9870616—

Reaction Steps

Compound 22 was prepared in a manner similar to that of compound 21 using 4-chlorobenzylamine instead of cyclopentylamine, MS 501.19 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045519B2
Source datasetuspto-grants-2015_06
ORD IDord-eaebf84a51c24f5e8eb2f9502ff6ac02
Source noteuspto-grants-2015_06