Sodium Azide → HCID 57707899, compound

Participants

Reaction Steps

To stirring solution of 8-chloro-3-(chloromethyl)-2-(2-fluorophenyl)quinoline (0.330 g, 1.08 mmol) in DMF was added sodium azide (0.561 g, 8.62 mmol), and the mixture stirred at room temperature. After 3 hours, the mixture was partitioned between CH2Cl2 and H2O. The organic layer was dried over MgSO4, filtered and concentrated under reduced pressure: LC-MS (ESI) m/z 313.0 [M+H]+. The crude product was carried on crude without purification for the next step.

Provenance & Evidence