Hydrochloric Acid → HCID 67387349, compound

Participants

Reaction Steps

The {4-[6-Butyl-5-(4-cyclohexyloxy-phenyl)-pyridazin-3-yloxy]-1-methyl-piperidin-3-yl}-methanol was dissolved in 4.0 M HCl in dioxane (2 mL) and evaporated the solvent, dried to provide the title compound (26 mg). LCMS: m/z 455 [M+1]. 1H NMR (400 MHz, CD3OD) δ 7.32 (2H, d), 7.03 (2H, d), 6.99 (1H, s), 5.58 (1H, s), 4.44-4.38 (1H, m), 3.66-3.62 (1H, m), 3.58-3.49 (1H, m), 2.96-2.80 (4H, m), 2.63-2.20 (7H, m), 2.08-1.90 (3H, m), 1.88-1.78 (2H, m), 1.62-1.20 (11H, m), 0.79 (3H, t).

Provenance & Evidence