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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2168948Generated: October 31, 2026

3-methoxy-N-(4-methoxybutyl)-2-nitroaniline → 6-Methoxy-2-(4-methoxybutylamino)aniline

https://huagongshe.com/reaction/2168948

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-methoxy-N-(4-methoxybutyl)-2-nitroanilineHCID 58355768—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
Product6-Methoxy-2-(4-methoxybutylamino)anilineHCID 58355726103.5%

Reaction Steps

3-Methoxy-N-(4-methoxybutyl)-2-nitroaniline (230 mg) was dissolved in methanol (30 ml), palladium-carbon (5%, 90 mg) was added, and the mixture was stirred for 2 hr under a hydrogen atmosphere. The reaction mixture was filtered through celite, and the filtrate was concentrated under reduced pressure to give the object product (210 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045436B2
Source datasetuspto-grants-2015_06
ORD IDord-36118869519c4b9e924a846dfec7570a
Source noteuspto-grants-2015_06