HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Isopropylamino)ethanol → N-(2-((tert-butyldimethylsilyl)oxy)ethyl)propan-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Isopropylamino)ethanol | HCID 7994 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | N-(2-(tert-Butyldimethylsilyloxy)ethyl)methylamine | HCID 16203640 | — |
| Product | N-(2-((tert-butyldimethylsilyl)oxy)ethyl)propan-2-amine | HCID 57917054 | 38% |
Reaction Steps
[2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-isopropyl-amine (8-b) (20 gm, 37.4%) was synthesized as a yellow liquid from 2-isopropylamino-ethanol (18-b) (25 g, 242.31 mmol) and tert-butyl-chloro-dimethyl-silane (25.5 g, 242.31 mmol) following the procedure as described for [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-methyl-amine (8-a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-6d1844a642a94b798d4c6f7abfcfd69c |
| Source note | uspto-grants-2015_06 |