HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178457484, compound → HCID 178457449, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178457484 | HCID 178457484 | — |
| Reactant | HCID 178484642 | HCID 178484642 | — |
| Product | HCID 178457449 | HCID 178457449 | 47% |
Reaction Steps
5-Benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid (2-hydroxyethyl)-isopropylamide (10-03) (650 mg, 47%) was synthesized as a yellow liquid from 5-benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-isopropylamide (9-03) (1.7 g, 38.16 mmol) following the procedure as described for 5-benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid (2-hydroxyethyl)-methyl-amide (10-01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-7e3590ec4d6147e59546c97866dd14b5 |
| Source note | uspto-grants-2015_06 |