HRID2169146

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)N1CCn2c(Cc3ccccc3-c3ccccc3)nc(=O)c(OCc3ccccc3)c2C1=O

HCID86725799

未命名化合物

结构：CN1CCn2c(Cc3ccccc3-c3ccccc3)nc(=O)c(O)c2C1=O

HCID86725801

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCn2c(Cc3ccccc3-c3ccccc3)nc(=O)c(O)c2C1=O

HCID86725803

未命名化合物

收率 19.1%

PROCEDURE

实验过程

6-Biphenyl-2-ylmethyl-9-hydroxy-2-isopropyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (12-03) (17 mg, 19%) was synthesized as an off-white solid from 9-benzyloxy-6-biphenyl-2-ylmethyl-2-isopropyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (11-03) (110 mg, 0.229 mmol) following the procedure as described for 6-biphenyl-2-ylmethyl-9-hydroxy-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (12-01).