(1-Phenylcyclopentyl)acetonitrile → HCID 86725806, compound

HRID 2169156Notes

Reaction equation

HRID 2169156 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([CH2:13]OS(C)(=O)=O)[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.C1(C2(C[C:31]#[N:32])CCCC2)C=CC=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([CH2:13][C:31]#[N:32])[CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 223258(1-Phenylcyclopentyl)acetonitrileHCID 86725805Methanesulfonic acid 1-(4-chlorophenyl)-cyclopentylmethyl ester

Product 1

HCID 86725806HCID 86725806, compoundYield 49.16%

Procedure

[1-(4-chlorophenyl)-cyclopentyl]-acetonitrile (25-02) (12 g, 49.16%) was synthesized from methanesulfonic acid 1-(4-chlorophenyl)-cyclopentylmethyl ester (24-02) (32 g, 111.11 mmol) as a colourless liquid following the procedure as described for 1-phenyl-cyclopentyl)-acetonitrile (25-01).

Sources & evidence

ORD record
ord-caea9cfba3414a45b665c0ea140e8f67
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

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