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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169157Generated: October 27, 2026

(1-Phenylcyclopentyl)acetonitrile → 2-(1-Phenyl-cyclopentyl)-acetamidine HCl salt

https://huagongshe.com/reaction/2169157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-Phenylcyclopentyl)acetonitrileHCID 223258—
Reactant2-(2'-Chloro-biphenyl-2-yl)-acetamidine hydrochloride saltHCID 86725783—
Product2-(1-Phenyl-cyclopentyl)-acetamidine HCl saltHCID 8672580777.7%

Reaction Steps

2-(1-Phenyl-cyclopentyl)-acetamidine HCl salt (26-01) (4.2 g, 77.7%) was synthesized from (1-phenyl-cyclopentyl)-acetonitrile (25-01) (4.2 g, 22.703 mmol) as a white gummy solid as a crude product following the procedure as described for 2-(2′-chloro-biphenyl-2-yl)-acetamidine hydrochloride salt (5-02).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-571c0a5794a14e1cb8664a6638d6ff3c
Source noteuspto-grants-2015_06