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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169162Generated: October 26, 2026

HCID 178450811, compound → HCID 178524871, compound

https://huagongshe.com/reaction/2169162

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178450811HCID 178450811—
ReactantHCID 178524878HCID 178524878—
ProductHCID 178524871HCID 17852487168.6%

Reaction Steps

5-Benzyloxy-2-[1-(4-chlorophenyl)-cyclopentylmethyl]-6-hydroxypyrimidine-4-carboxylic acid (28-02) (7.3 g, 68.6%) was synthesized from 5-benzyloxy-2-[1-(4-chlorophenyl)-cyclopentylmethyl]-6-hydroxypyrimidine-4-carboxylic acid tert-butyl ester (27-02) (12 g, 34.24 mmol) as a white solid following the procedure as described for 5-benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid (7-01).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-9c958fdd724f44ffb92f8420489c19e4
Source noteuspto-grants-2015_06