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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169165Generated: November 2, 2026

HCID 178484642, compound → HCID 178484638, compound

https://huagongshe.com/reaction/2169165

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178484642HCID 178484642—
ReactantHCID 178484769HCID 178484769—
ProductHCID 178484638HCID 17848463874.8%

Reaction Steps

5-Benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid (2-hydroxyethyl)-methyl-amide (30-01) (600 mg, 74.75%) was synthesized from 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-methyl-amide (29-01) (1.0 g, 1.739 mmol) as a yellow solid following the procedure as described for 5-benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid (2-hydroxyethyl)-methyl-amide (10-01).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-b87d8aeffa5a44eb8eebe99dd0be6f7b
Source noteuspto-grants-2015_06