HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178484642, compound → HCID 178484638, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178484642 | HCID 178484642 | — |
| Reactant | HCID 178484769 | HCID 178484769 | — |
| Product | HCID 178484638 | HCID 178484638 | 74.8% |
Reaction Steps
5-Benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid (2-hydroxyethyl)-methyl-amide (30-01) (600 mg, 74.75%) was synthesized from 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-methyl-amide (29-01) (1.0 g, 1.739 mmol) as a yellow solid following the procedure as described for 5-benzyloxy-2-biphenyl-2-ylmethyl-6-hydroxypyrimidine-4-carboxylic acid (2-hydroxyethyl)-methyl-amide (10-01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-b87d8aeffa5a44eb8eebe99dd0be6f7b |
| Source note | uspto-grants-2015_06 |