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HRID2169172

反应详情

EQUATION

反应方程式

HRID 2169172 的结构方程式

REACTANTS

反应物

2
结构：CN1CCn2c(Cc3ccccc3-c3ccccc3)nc(=O)c(O)c2C1=O
HCID86725801

未命名化合物

结构：CN1CCn2c(CC3(c4ccc(Cl)cc4)CCCC3)nc(=O)c(OCc3ccccc3)c2C1=O
HCID86725822

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCn2c(CC3(c4ccc(Cl)cc4)CCCC3)nc(=O)c(O)c2C1=O
HCID86725825

未命名化合物

收率 66.3%

PROCEDURE

实验过程

6-[1-(4-chlorophenyl)-cyclopentylmethyl]-9-hydroxy-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (32-02) (296 mg, 66.3%) was synthesized from 9-benzyloxy-6-[1-(4-chlorophenyl)cyclopentylmethyl]-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (31-02) (500 mg, 1.151 mmol) as an off-white solid following the procedure as described for 6-biphenyl-2-ylmethyl-9-hydroxy-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (12-01).