HRID2169173

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN1CCn2c(Cc3ccccc3-c3ccccc3)nc(=O)c(O)c2C1=O

HCID86725801

未命名化合物

结构：CC(C)N1CCn2c(CC3(c4ccc(Cl)cc4)CCCC3)nc(=O)c(OCc3ccccc3)c2C1=O

HCID86725823

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCn2c(CC3(c4ccc(Cl)cc4)CCCC3)nc(=O)c(O)c2C1=O

HCID86725826

未命名化合物

收率 62.8%

PROCEDURE

实验过程

6-[1-(4-chlorophenyl)-cyclopentylmethyl]-9-hydroxy-2-isopropyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (32-03) (465 mg, 62.8%) was synthesized from 9-benzyloxy-6-[1-(4-chlorophenyl)-cyclopentylmethyl]-2-isopropyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (31-03) (900 mg, 1.779 mmol) as an off-white solid following the procedure as described for 6-biphenyl-2-ylmethyl-9-hydroxy-2-methyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (12-01).