HRID2169226

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)N1CCn2c(Cc3cccc(Cl)c3Cl)nc(=O)c(O)c2C1=O

HCID86725867

未命名化合物

结构：CC(C)N1CCn2c(Cc3ccccc3-c3ccncc3)nc(=O)c(OCc3ccccc3)c2C1=O

HCID86725873

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCn2c(Cc3ccccc3-c3ccncc3)nc(=O)c(O)c2C1=O

HCID86725874

未命名化合物

收率 14.8%

PROCEDURE

实验过程

9-Hydroxy-2-isopropyl-6-(2-pyridin-4-yl-benzyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (154) (30 mg, 14.77%) as a light yellow solid was synthesized from 9-benzyloxy-2-isopropyl-6-(2-pyridin-4-yl-benzyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (153) (250 mg, 0.52 mmol) following the procedure as described for 6-(2,3-dichlorobenzyl)-9-hydroxy-2-isopropyl-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (135).