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HRID2169238

反应详情

EQUATION

反应方程式

HRID 2169238 的结构方程式

REACTANTS

反应物

2
结构：CC(C)N1CCn2c(Cc3ncccc3-c3ccccc3)nc(=O)c(OCc3ccccc3)c2C1=O
HCID86725886

未命名化合物

结构：CC(C)N1CCn2c(CC3(c4ccc(C(F)(F)F)cc4)CCCC3)nc(=O)c(O)c2C1=O
HCID86725888

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N1CCn2c(Cc3ncccc3-c3ccccc3)nc(=O)c(O)c2C1=O
HCID86725887

未命名化合物

收率 43.9%

PROCEDURE

实验过程

9-Hydroxy-2-isopropyl-6-(3-phenyl-pyridin-2-ylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (168) (12 mg, 40.98%) as a light yellow solid was synthesized from 9-benzyloxy-2-isopropyl-6-(3-phenyl-pyridin-2-ylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (167) (36 mg, 0.07 mmol) following the procedure as described for 9-hydroxy-2-isopropyl-6-[1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl]-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (168).