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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169255Generated: October 30, 2026

1,4-Dibromobutane → 1-(2-Naphthyl)cyclopentanecarbonitrile

https://huagongshe.com/reaction/2169255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
Reactant2-NaphthylacetonitrileHCID 82008—
Reactant1-(2,5-Dichlorophenyl)cyclopentane-1-carbonitrileHCID 75426037—
Product1-(2-Naphthyl)cyclopentanecarbonitrileHCID 8672590675.5%

Reaction Steps

1-Naphthalen-2-yl-cyclopentanecarbonitrile (211) (25.0 g, 75.46%) was synthesized as a white solid from naphthalen-2-yl-acetonitrile (210) (25.0 g, 149.7 mmol) and 1,4-dibromobutane (17.8 mL, 149.7 mmol) following the procedure described for 1-(2,5-dichlorophenyl)-cyclopentanecarbonitrile (198).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-a6df6933a2ed47829ca005d2d3237b8c
Source noteuspto-grants-2015_06