[1-(2,5-Dichlorophenyl)-cyclopentyl]-methanol → (1-Naphthalen-2-yl-cyclopentyl)-methanol

HRID 2169257Notes

Reaction equation

HRID 2169257 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH:16]=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12]1.ClC1C=CC(Cl)=CC=1C1(CO)CCCC1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH2:16][OH:17])[CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 86725895[1-(2,5-Dichlorophenyl)-cyclopentyl]-methanolHCID 867259071-Naphthalen-2-yl-cyclopentanecarbaldehyde

Product 1

HCID 86725908(1-Naphthalen-2-yl-cyclopentyl)-methanolYield 99%

Procedure

(1-Naphthalen-2-yl-cyclopentyl)-methanol (213) (22.0 g, crude) was synthesized as a colourless liquid from 1-naphthalen-2-yl-cyclopentanecarbaldehyde (212) (22.0 g, 98.21 mmol) following the procedure described for 1-(2,5-dichlorophenyl)-cyclopentane-methanol (200).

Sources & evidence

ORD record
ord-c274091f23d3449a9ef93bd1750e23cb
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

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