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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169260Generated: November 1, 2026

2-[1-(2,5-Dichlorophenyl)-cyclopentyl]-acetamidine hydrochloride → 2-(1-Naphthalen-2-yl-cyclopentyl)-acetamidine hydrochloride

https://huagongshe.com/reaction/2169260

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[1-(2,5-Dichlorophenyl)-cyclopentyl]-acetamidine hydrochlorideHCID 86725898—
Reactant(1-Naphthalen-2-yl-cyclopentyl)-acetonitrileHCID 86725910—
Product2-(1-Naphthalen-2-yl-cyclopentyl)-acetamidine hydrochlorideHCID 86725911—

Reaction Steps

2-(1-Naphthalen-2-yl-cyclopentyl)-acetamidine hydrochloride (216) (5.0 g, crude) was synthesized as a white solid from (1-naphthalen-2-yl-cyclopentyl)-acetonitrile (215) (5.0 g, 21.27 mmol) following the procedure described for the HCl-salt of 2-[1-(2,5-dichlorophenyl)-cyclopentyl]-acetamidine hydrochloride (203).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-bf7c41fc323f480a8aa230ff6095a5d0
Source noteuspto-grants-2015_06