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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169262Generated: October 31, 2026

HCID 178450802, compound → HCID 178524862, compound

https://huagongshe.com/reaction/2169262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178450802HCID 178450802—
ReactantHCID 178524875HCID 178524875—
ProductHCID 178524862HCID 178524862112.3%

Reaction Steps

5-Benzyloxy-6-hydroxy-2-(1-naphthalen-2-yl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid (218) (300.0 mg, crude) was synthesized as a white solid from 5-benzyloxy-6-hydroxy-2-(1-naphthalen-2-yl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid tert-butyl ester (217) (300.0 mg, 0.588 mmol) following the procedure described for 5-benzyloxy-2-[1-(2,5-dichlorophenyl)-cyclopentylmethyl]-6-hydroxypyrimidine-4-carboxylic acid (205).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-690210a29a864c0d95b3b7dd048974b6
Source noteuspto-grants-2015_06