HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → [1-(4-Bromophenyl)cyclopentyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 1-(4-Bromophenyl)-cyclopentanecarbaldehyde | HCID 22502930 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [1-(4-Bromophenyl)cyclopentyl]methanol | HCID 67480063 | — |
Reaction Steps
To a stirred solution of 1-(4-bromophenyl)-cyclopentanecarbaldehyde (225) (51.0 g, 201.47 mmol) in methanol (400 mL), was added NaBH4 (15.31 g, 402.94 mmol) portion-wise at 0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-0a963ea57c0f4f548b7b1b67435917ea |
| Source note | uspto-grants-2015_06 |