HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178455274, compound → HCID 178519964, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178455274 | HCID 178455274 | — |
| Reactant | HCID 178519962 | HCID 178519962 | — |
| Product | HCID 178519964 | HCID 178519964 | 89.5% |
Reaction Steps
This compound was prepared following the same method as described for 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid cyclopropyl-(2-hydroxyethyl)-amide (285) from 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentyl-amide (288) (250 mg, 0.39 mmol). The product was obtained as an off-white sticky solid (180 mg, 87.83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-73d19c786a824b288d8917e64e4c4c62 |
| Source note | uspto-grants-2015_06 |