Pivalaldehyde → [2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-(2,2-dimethyl-propyl)-amine

HRID 2169335Notes

Reaction equation

HRID 2169335 reaction equation
[Si:1]([O:8][CH2:9][CH2:10][NH:11]C1CCCC1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[CH3:17][C:18]([CH3:22])([CH3:21])[CH:19]=O.[Si](OCCN)(C(C)(C)C)(C)C>>[Si:1]([O:8][CH2:9][CH2:10][NH:11][CH2:19][C:18]([CH3:22])([CH3:21])[CH3:17])([C:4]([CH3:6])([CH3:7])[CH3:5])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 12417PivalaldehydeHCID 529218(2-Aminoethoxy)(tert-butyl)dimethylsilaneHCID 86725959[2-(Tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentylamine

Product 1

HCID 86725974[2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-(2,2-dimethyl-propyl)-amine

Procedure

This compound was prepared following the same method as described for [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentyl-amine (8e) from 2,2-dimethyl-propionaldehyde (1 g, 11.61 mmol) and 2-(tert-butyl-dimethylsilanyloxy)-ethylamine (8c) (2.0 g, 11.6 mmol) as colorless oil (1.1 g, 38.6%).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-6634f52311684203be724b80b6aa72c8
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

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