HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarboxaldehyde → [2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-cyclopropylmethyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarboxaldehyde | HCID 123114 | — |
| Reactant | (2-Aminoethoxy)(tert-butyl)dimethylsilane | HCID 529218 | — |
| Reactant | [2-(Tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentylamine | HCID 86725959 | — |
| Product | [2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-cyclopropylmethyl-amine | HCID 69361897 | 28.51% |
Reaction Steps
This compound was prepared following the same method as described for [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentyl-amine (8e) from cyclopropanecarbaldehyde (300 mg, 4.23 mmol) and 2-(tert-butyl-dimethylsilanyloxy)-ethylamine (8c) (975 mg, 5.56 mmol). The product was obtained as a colourless liquid (280 mg, 28.51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-92c8c738b18e41aaadd7e01f0653ea18 |
| Source note | uspto-grants-2015_06 |