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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169347Generated: November 1, 2026

HCID 178455275, compound → HCID 178519965, compound

https://huagongshe.com/reaction/2169347

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178455275HCID 178455275—
ReactantHCID 178519962HCID 178519962—
ProductHCID 178519965HCID 17851996590.6%

Reaction Steps

This compound was prepared following the same method as described for 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid cyclopropyl-(2-hydroxyethyl)-amide (285) from 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-(tetrahydro-pyran-4-yl)-amide (308) (540 mg, 0.83 mmol). The product was obtained as a white solid (400 mg, 89.99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-1148ef8f95e74db186d349d6e6cbd582
Source noteuspto-grants-2015_06