HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178455275, compound → HCID 178519965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178455275 | HCID 178455275 | — |
| Reactant | HCID 178519962 | HCID 178519962 | — |
| Product | HCID 178519965 | HCID 178519965 | 90.6% |
Reaction Steps
This compound was prepared following the same method as described for 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid cyclopropyl-(2-hydroxyethyl)-amide (285) from 5-benzyloxy-6-hydroxy-2-(1-phenyl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-(tetrahydro-pyran-4-yl)-amide (308) (540 mg, 0.83 mmol). The product was obtained as a white solid (400 mg, 89.99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-1148ef8f95e74db186d349d6e6cbd582 |
| Source note | uspto-grants-2015_06 |