HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzaldehyde → [2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-(4-fluoro-benzyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | (2-Aminoethoxy)(tert-butyl)dimethylsilane | HCID 529218 | — |
| Reactant | [2-(Tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentylamine | HCID 86725959 | — |
| Product | [2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-(4-fluoro-benzyl)-amine | HCID 59688027 | 35.03% |
Reaction Steps
This compound was prepared following the same method as described for [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopentyl-amine (8e) from 4-fluorobenzaldehyde (1 g, 8.06 mmol) and 2-(tert-butyl-dimethylsilanyloxy)-ethylamine (8c) (1.8 g, 10.48 mmol). The product was obtained as a light yellow liquid (800 mg, 35.03%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09045486B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-0443ed13e21440c3bff7b3c18fc0528c |
| Source note | uspto-grants-2015_06 |