[2-(tert-Butyl-dimethylsilanyloxy)-ethyl]-cyclopropylmethyl-amine → HCID 178455247, compound

Participants

Reaction Steps

This compound was prepared by following the same method as described for 5-benzyloxy-6-hydroxy-2-(1-naphthalen-1-yl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-methyl-amide (350) from ‘5-benzyloxy-6-hydroxy-2-(1-naphthalen-1-yl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid (345) (225 mg, 0.50 mmol) and [2-(tert-butyl-dimethylsilanyloxy)-ethyl]-cyclopropylmethyl-amine (8i) (170 mg, 0.74 mmol). The yield was 307 mg, 93% of a white solid.

Provenance & Evidence