HRID2169406

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C1NCCn2c(CC3(c4cccc5ccccc45)CCCC3)nc(=O)c(O)c21

HCID86726018

未命名化合物

结构：O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4cccc5ccccc45)CCCC3)n2CCN1Cc1ccccc1

HCID86726037

未命名化合物

PRODUCTS

生成物

结构：O=C1c2c(O)c(=O)nc(CC3(c4cccc5ccccc45)CCCC3)n2CCN1Cc1ccccc1

HCID86726038

未命名化合物

PROCEDURE

实验过程

This compound was prepared following the same method as described for pure 9-hydroxy-6-(1-naphthalen-1-yl-cyclopentylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (349) from 2-benzyl-9-benzyloxy-6-(1-naphthalen-1-yl-cyclopentylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (372) (110 mg, 0.19 mmol). The yield was 35 mg, 47%, of a light brown solid.

WORKUP

后处理

customThis compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c7fc05f1add845be93c64831f28d26ee
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09045486B2
来源说明: uspto-grants-2015_06

反应 SMILES

OC1C(=O)N=C(CC2(C3C4C(=CC=CC=4)C=CC=3)CCCC2)N2CCNC(=O)C=12.[CH2:30]([N:37]1[CH2:71][CH2:70][N:40]2[C:41]([CH2:54][C:55]3([C:60]4[C:69]5[C:64](=[CH:65][CH:66]=[CH:67][CH:68]=5)[CH:63]=[CH:62][CH:61]=4)[CH2:59][CH2:58][CH2:57][CH2:56]3)=[N:42][C:43](=[O:53])[C:44]([O:45]CC3C=CC=CC=3)=[C:39]2[C:38]1=[O:72])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH2:30]([N:37]1[CH2:71][CH2:70][N:40]2[C:41]([CH2:54][C:55]3([C:60]4[C:69]5[C:64](=[CH:65][CH:66]=[CH:67][CH:68]=5)[CH:63]=[CH:62][CH:61]=4)[CH2:59][CH2:58][CH2:57][CH2:56]3)=[N:42][C:43](=[O:53])[C:44]([OH:45])=[C:39]2[C:38]1=[O:72])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1