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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169489Generated: November 1, 2026

HCID 178450814, compound → HCID 178524874, compound

https://huagongshe.com/reaction/2169489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178450814HCID 178450814—
ReactantHCID 178524870HCID 178524870—
ProductHCID 178524874HCID 178524874—

Reaction Steps

5-(benzyloxy)-2-((1-(3,5-bis(trifluoromethyl)phenyl)cyclopentyl)methyl)-6-hydroxypyrimidine-4-carboxylic acid (462) was synthesized as a white solid from tert-butyl 5-(benzyloxy)-2-((1-(3,5-bis(trifluoromethyl)phenyl)cyclopentyl)methyl)-6-hydroxypyrimidine-4-carboxylate (461) following the procedure described for 5-benzyloxy-2-[1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl]-6-hydroxypyrimidine-4-carboxylic acid (244).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-7677638aeccc4fc1a7b8d4fe5a6137c8
Source noteuspto-grants-2015_06