1-(4-Trifluoromethyl-phenyl)-cyclopentanecarbaldehyde → 1-(3-(Trifluoromethyl)phenyl)cyclopentanecarbaldehyde

HRID 2169495Notes

Reaction equation

HRID 2169495 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([C:9]2([C:14]#N)[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1.FC(F)(F)C1C=CC(C2(C=[O:32])CCCC2)=CC=1>>[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([C:9]2([CH:14]=[O:32])[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 218996431-(4-Trifluoromethyl-phenyl)-cyclopentanecarbaldehydeHCID 431190351-(3-(Trifluoromethyl)phenyl)cyclopentanecarbonitrile

Product 1

HCID 838060911-(3-(Trifluoromethyl)phenyl)cyclopentanecarbaldehyde

Procedure

1-(3-(Trifluoromethyl)phenyl)cyclopentanecarbaldehyde (469) was synthesized from 1-(3-(trifluoromethyl)phenyl)cyclopentanecarbonitrile (468) following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentanecarbaldehyde (238).

Sources & evidence

ORD record
ord-fa82f43ab6cf42a49afbfcd5ca7410c1
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

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