1-(3-(Trifluoromethyl)phenyl)cyclopentanecarbaldehyde → (1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methanol

HRID 2169496Notes

Reaction equation

HRID 2169496 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([C:9]2([CH:14]=[O:15])[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1.FC(F)(F)C1C=CC(C2(CO)CCCC2)=CC=1>>[F:1][C:2]([F:16])([F:17])[C:3]1[CH:4]=[C:5]([C:9]2([CH2:14][OH:15])[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 838060911-(3-(Trifluoromethyl)phenyl)cyclopentanecarbaldehydeHCID 86725928[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-methanol

Product 1

HCID 86726118(1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methanol

Procedure

(1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methanol (470) was synthesized from 1-(3-(trifluoromethyl)phenyl)cyclopentanecarbaldehyde (469) following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentane-methanol (239).

Sources & evidence

ORD record
ord-b07f18d9db7b48d58ff2da8fac8763c6
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

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