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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169500Generated: November 2, 2026

HCID 178457441, compound → HCID 178457439, compound

https://huagongshe.com/reaction/2169500

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178457441HCID 178457441—
ReactantHCID 178457475HCID 178457475—
ProductHCID 178457439HCID 178457439—

Reaction Steps

5-(Benzyloxy)-6-hydroxy-N-(2-hydroxyethyl)-N-isopropyl-2-((1-(3-(trifluoromethyl)phenyl)cyclo-pentyl)methyl)pyrimidine-4-carboxamide (477) was synthesized from 5-(benzyloxy)-N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-6-hydroxy-N-isopropyl-2-((1-(3-(trifluoromethyl)phenyl)cyclo-pentyl)methyl)pyrimidine-4-carboxamide (476) following the procedure described for 5-benzyloxy-2-[1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl]-6-hydroxypyrimidine-4-carboxylic acid (2-hydroxyethyl)-isopropylamide (246).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-fe082f9a27ab4e4681fe53149ca386e1
Source noteuspto-grants-2015_06