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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169503Generated: October 31, 2026

1,4-Dibromobutane → 1-(3,4-Dichlorophenyl)cyclopentanecarbonitrile

https://huagongshe.com/reaction/2169503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
Reactant(3,4-Dichlorophenyl)acetonitrileHCID 76690—
Reactant1-(4-(Trifluoromethyl)phenyl)cyclopentanecarbonitrileHCID 21899624—
Product1-(3,4-Dichlorophenyl)cyclopentanecarbonitrileHCID 21258476—

Reaction Steps

1-(3,4-dichlorophenyl)cyclopentanecarbonitrile (481) was synthesized from 2-(3,4-dichlorophenyl)acetonitrile (480) and 1,4-dibromobutane following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentanecarbonitrile (237).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-b07dbf442b3a4ffb9dbbd27bb9786399
Source noteuspto-grants-2015_06