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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169507Generated: October 29, 2026

[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetonitrile → 2-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrile

https://huagongshe.com/reaction/2169507

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetonitrileHCID 86725930—
Reactant(1-(3,4-Dichlorophenyl)cyclopentyl)methyl methanesulfonateHCID 86726127—
Product2-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrileHCID 86726128—

Reaction Steps

2-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrile (485) was synthesized from (1-(3,4-dichlorophenyl)cyclopentyl)methyl methanesulfonate (484) following the procedure described for [1-(4-trifluoromethyl-phenyl)cyclopentyl]-acetonitrile (241).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-2b7bce225d7d480e99b9b3605519497d
Source noteuspto-grants-2015_06