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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2169515Generated: November 1, 2026

1,4-Dibromobutane → 1-(3-Chlorophenyl)cyclopentanecarbonitrile

https://huagongshe.com/reaction/2169515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
Reactantm-ChlorophenylacetonitrileHCID 73722—
Reactant1-(4-(Trifluoromethyl)phenyl)cyclopentanecarbonitrileHCID 21899624—
Product1-(3-Chlorophenyl)cyclopentanecarbonitrileHCID 15742719—

Reaction Steps

1-(3-Chlorophenyl)cyclopentanecarbonitrile (494) was synthesized from 2-(3-chlorophenyl)acetonitrile (493) and 1,4-dibromobutane following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentanecarbonitrile (237).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09045486B2
Source datasetuspto-grants-2015_06
ORD IDord-d38b2076cc574b7bbb235bfac3f1f18a
Source noteuspto-grants-2015_06