1-(3-Chlorophenyl)cyclopentanecarbaldehyde → (1-(3-Chlorophenyl)cyclopentyl)methanol
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2([CH:13]=[O:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1.FC(F)(F)C1C=CC(C2(CO)CCCC2)=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2([CH2:13][OH:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
(1-(3-Chlorophenyl)cyclopentyl)methanol (496) was synthesized from 1-(3-chlorophenyl)phenyl)cyclopentanecarbaldehyde (495) following the procedure described for 1-(4-trifluoromethyl-phenyl)-cyclopentane-methanol (239).
Sources & evidence
- ORD record
- ord-4269d48073a3454a93356e57590f51fe
- Source dataset
- uspto-grants-2015_06
- Patent number
- US09045486B2
Reaction notes
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