(1-(3-Chlorophenyl)cyclopentyl)methanol → (1-(3-Chlorophenyl)cyclopentyl)methyl methanesulfonate

HRID 2169518Notes

Reaction equation

HRID 2169518 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2([CH2:13][OH:14])[CH2:12][CH2:11][CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1.FC(F)(F)C1C=CC(C2(C[O:29][S:30]([CH3:33])(=O)=[O:31])CCCC2)=CC=1>>[CH3:33][S:30]([O:14][CH2:13][C:8]1([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[CH2:12][CH2:11][CH2:10][CH2:9]1)(=[O:31])=[O:29]

Participants

3

Reactant 2

HCID 83688880(1-(3-Chlorophenyl)cyclopentyl)methanolHCID 86725929Methanesulfonic acid 1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl ester

Product 1

HCID 86726139(1-(3-Chlorophenyl)cyclopentyl)methyl methanesulfonate

Procedure

(1-(3-Chlorophenyl)cyclopentyl)methyl methanesulfonate (497) was synthesized from (1-(3-chlorophenyl)cyclopentyl)methanol (496) following the procedure described for Methanesulfonic acid 1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl ester (240).

Sources & evidence

ORD record
ord-ee05be5ee5d04c8886f42dfabe894293
Source dataset
uspto-grants-2015_06
Patent number
US09045486B2

Reaction notes

Loading…